Thousands of tonnes of extra nuclear material is destined to pass through the West Midlands, CND campaigners claim – leading them to step up actions in the region.
Trains carrying nuclear waste already travel on freight lines through Birmingham at least once a week.
In addition, military convoys carrying warheads pass within ten miles of Birmingham along the M40, M42, M5 and M6 motorways about six times a year.
CND activists now believe the scale of nuclear traffic is set to increase drastically.
They highlight an imminent decision on a major modernisation of Britain's deterrent system, Trident, and proposals to replace outdated nuclear power stations.
Kate Hudson, head of CND, said: "Which ever way you look at it, we are going to have an increase in nuclear traffic.
"On the question of nuclear weapons, the main route is from Aldermaston in Berkshire, where the warheads are made, going up through the West Midlands on the M40 and M6 to Sellafield.
"At the moment there is massive expansion work taking place at Aldermaston, comparable with the work on the fifth terminal at Heathrow.
"If the Government undertakes the building of new warheads, we anticipate there will be greatly increased transport through the region."
Ms Hudson also claimed construction of a new generation of nuclear power stations would greatly increase the amount of radio active material passing through the West Midlands by rail.
Ms Hudson said: "This is a once-in-a-generation chance for
Britain to say it doesn't want to pursue security based on weapons of mass destruction."
Convoys carrying nuclear materials for use in nuclear warheads travel between Aldermaston and Sellafield in Cumbria and Trident's headquarters in Scotland.
Trident's four submarines carry nearly 200 nuclear warheads between them. Each warhead has an explosive power of up to 100 kilotons – eight times the power of the atomic bomb that was dropped on Hiroshima.
The route taken by trains carrying waste from nuclear power plants includes the Birmingham suburbs of Barnt Green, Kings Norton, Kings Heath, Moseley, Saltley and Washwood Heath.
According to Jenny Maxwell, regional chairman of CND for the West Midlands, the transportation posed a huge risk to the public.
"The stuff on the trains is highly radio active from nuclear power stations and they are coming through the region," she said.
"But we aren't given the facts. How many people are aware that nuclear waste is coming through Birmingham?"
The Ministry of Defence yesterday said the chances of an accident serious enough to cause damage to a nuclear weapon during transport was "extremely remote".
"The MoD’s nuclear safety record is second to none and we do everything possible to protect our nuclear weapons convoys," said a spokeswoman.
"Modern nuclear weapons convoys are inherently robust and resistant to damage. They are protected during transport by both protective packaging and the specially designed vehicles in which they are carried."
Concern over the underground dumping of nuclear waste in the West Midlands was raised last month.
It followed recommendations by the Committee on Radioactive Waste Management that underground disposal was the best way forward. The Government is expected to endorse the findings. It will mean Nirex, the Government-owned company responsible for the management of radioactive waste, will begin looking for sites.
Campaigners fear a hit-list of 537 sites identified in the late 80s including 12 in Warwickshire and one in Solihull, will be revisited.
Last night Direct Rail Services Ltd, the company responsible for moving used nuclear fuel by rail, stressed its exemplary safety record.
"This material has been transported in this way since 1962, travelling over eight million miles without any incident involving the release of radioactive material," it said.
Spent fuel is transported in flasks made of forged steel, weighing more than 50 tonnes and over 30cm thick.
With her roll-neck woolly jumper, Jenny Maxwell looks the part. She wears a badge bearing the familiar CND logo – a mixture of the military symbols for N and D representing "nuclear" and "disarmament".
But her involvement in the anti-nuclear movement is much more than just an image. At 65 and a grandmother of four she might well have hung up her campaigning boots long ago, if it wasn't for her strong conviction.
"I joined CND when I was at school but then I laspsed," she said. "I got back into it because a friend took me on a demonstration in 1980. I thought 'here is something I feel strongly about. It is wrong."
From there, she joined her local CND group in Harborne, rising to treasurer for the West Midlands region and ending up its chairman, a position which she still holds.
"The more I found out about it, the more I feel it is wrong that anyone in the world has nuclear weapons. My reason for opposing them is I think they are fundamentally immoral and illegal. I don't think it is right that any one country should have the capacity to destroy the whole world."
One of the things that depresses her, though, is the attitude of the current Government - led by a former CND member.
"Although we never expected in 1997 they would get rid of everything, we did expect them to be better than they have been," she said.
With a major programme to replace Britain's nuclear deterrent Trident expected to be announced soon and the prospect of building the next generation of nuclear power stations on the horizon, the situation is likely to get worse.
Ms Maxwell believes there are clear signs that Britain is entering a new nuclear age by the massive investment at Aldermaston in Berkshire, headquarters of the UK's Atomic Weapons Establishment.
The Ministry of Defence stresses that no decisions have yet been taken on any replacement for Trident, "either in principle or in detail".
Ms Maxwell believes the reasons Britain gives for having nuclear weapons is flawed. "They say it is a political weapon. They almost agree it has no military use but it gives political clout.
"They say it is essential for our security, but how then can they possibly say it is not essential for Iran's security? It is near India, Pakistan, Russia, China and India who all have nuclear weapons."
The prospect currently being tabled of nuclear waste being buried underground also frightens her.
"No one knows what is going to happen in one thousand years time. If they are disposing waste underground in mid Wales and it starts leaking into the Elan Valley, Birmingham could have radioactive water."
She describes proposals by the Government to give local authorities cash incentives to bury nuclear waste as "bribery" and believes the billions spent on nuclear missiles and power stations could be better used on more pressing concerns.
"The three things the Government says are threatening us are global warming, the environment and terrorism.
"That is why it is so absurd that we are looking at spending billions on the new Trident system. All this scientific expertise is being put into killing people when it should be put into saving the environment."