Two drivers died in separate crashes and an oil tanker overturned as freezing conditions swept the region over the weekend.
A man died in a two-car smash in Portland Road, Bearwood, Birmingham, at 5.30am on Sunday, while just hours earlier, a 21-year-old man from Lichfield suffered fatal injuries when his black Citroen Saxo swerved off the A38 southbound carriageway near Barton under Needwood, Staffordshire, and hit a tree.
He was freed from the wreckage by fire crews but later died at Coventry’s Walsgrave Hospital.
The M5 was also closed in both directions in Worcestershire after a petrol tanker overturned in the morning.
Police officers closed off roads at all the crash sites as they spent hours examining the areas to determine whether icy conditions had played a part as temperatures plummeted to as low as -6C at the weekend.
John Hawker, a West Midlands Ambulance Service spokesman, said the accident in Bearwood had involved two cars in a “significant collision”.
“The occupant of one car had sustained serious injuries and unfortunately despite the best efforts of ambulance crews nothing could be done to save the man and he was confirmed dead at the scene,” said Mr Hawker.
“The occupants of the other vehicle were checked over at the scene by ambulance crews but did not require hospital treatment.”
The M5 was closed in both directions between junctions 8 and 7 near the village of Kempsey in Worcestershire at 8.20am following the tanker spillage.
Emergency crews discovered the driver had escaped injury in his cab, which remained upright, but the trailer had overturned, spewing fuel across both carriageways.
Fire crews closed off a 400-metre stretch of the motorway for hours to make the carriageways safe for traffic.
Frost, ice and even snow in some areas of Britain made journeys more hazardous than normal.
Icy conditions even halted a number of FA Cup matches in the Midlands over the weekend including the eagerly awaited clash between Birmingham City and Wolverhampton Wanderers at St Andrew's.
Weather forecasters have warned that there will be severe frost towards evening and early morning for the next few days.