Two teenagers have died and two people are in hospital following a three-vehicle crash, on Monday night.
The male driver of a white Peugeot 306, believed to be aged 19, was pronounced dead at the scene, following a collision on the A49 in south Shropshire.
A passenger in the car, a teenage boy, was taken to the Royal Shrewsbury Hospital for treatment, but died Tuesday morning.
Another passenger sustained serious injuries and was transferred to University Hospital Coventry and Warwickshire. The casualties have not yet been named, but police said both are believed to be from the south Shropshire area.
A spokesman for West Mercia Police could not confirm the age of the passenger who died.
The Peugeot, travelling south on the A49, was in collision with a red Jeep Cherokee and a white Vauxhall Vivaro van at around 9.45pm.
The Jeep and the van were travelling northbound, towards Shrewsbury, when the three vehicles collided about a mile north of the town of Craven Arms. The drivers of the Jeep and the van were uninjured but both were treated at the scene for shock.
A 53-year-old female passenger in the Jeep was taken to the Royal Shrewsbury Hospital with a suspected broken wrist.
A West Midlands Ambulance Service spokesman said a passing ambulance "came across the scene" and called for two more crews to attend.
The A49 was closed overnight and diversions were set up.
A police spokesman said: "We are anxious to hear from anyone who saw the collision or the circumstances leading up to it."
He added that it may be several days before the teenage victims are named.
Their families have been informed but formal identification is yet to take place, the spokesman said.
Witnesses are urged to contact Ludlow police station on 08457 444 888