Smokers across the Midlands who have tried and failed to quit are being urged to try again on No Smoking Day.
In the past 50 years, smoking-related illnesses have killed 6.3 million people in Britain, with the West Midlands being one of the worst hit regions.
On Wednesday local NHS stop smoking services will stage events across the region to encourage smokers to give up for good.
Lorraine Darby, a motheroftwo and smoker for 20 years, is just one of the thousands who will commit to quitting - despite seven previous attempts to do so.
The 57-year-old, a cardiac liaison nurse for Rowley Regis and Tipton Primary Care Trust, puffs her way through 20 cigarettes a day.
For an added incentive, Mrs Darby is asking colleagues to sponsor her efforts in order to raise money for Comic Relief.
She said: "My family are moaning at me, especially my grandson, and No Smoking Day plus Comic Relief seemed like a good opportunity to quit for good.
"One of the main causes of coronary heart disease is smoking so it seems hypocritical of me to be encouraging them to be healthier when I'm a smoker myself.
"I want a fresh start and I want to look forward to a healthy old age. It will be a struggle, but I know I can do it with the support of my 'fairy godmother'."
The "fairy godmother" is Sue Lewis, a nurse adviser from Sandwell Stop Smoking Service, who will be helping Mrs Darby quit successfully.
Ms Lewis, a reformed smoker, said: "I'll be supporting Lorraine as much as I can, as I do with all my clients.
"She can look forward to lots more energy and fresher breath as well as longer-term health benefits."
* For information on NHS stop smoking services go to givingupsmoking.co.uk or call the national QuitLine on 0800 169 0169. Details of No Smoking Day events can be found at nosmokingday.org.uk