A bumper team from Queen Alexandra College in Harborne will be taking on the Morrisons Great Birmingham 10k as it bids to raise funds and awareness of the national charity.
A total of 29 runners with a wide range of ages and abilities will strap on their running shoes next weekend for the race including staff from the college and its fitness centre, students and family members.
Based on Court Oak Road in Harborne, the specialist national college for people with disabilities also manages a number of off-site hubs and social enterprises.
These include a Bearwood bicycle shop iCycle, the neighbouring café Coffee Junction and Umberslade Nurseries in Selly Oak.
Sarah Caldwell, fundraising and grants manager at the college, said: "It's taken quite a bit of co-ordinating but we have a great team.
"We're doing it to raise money and awareness but we also want people to have fun."
The Great Birmingham 10k takes place on May 3 and is being supported by the Birmingham Post.
Any size of company can take part in the Business Challenge and enter male, female or mixed teams which must have a minimum of two men and two women.
Teams must have four to eight runners but a company can enter as many teams as it wishes. All participants must be 16 years of age or over on race day.
Prizes will be awarded to the first three teams in each category. For more details and to enter visit www.greatrun.org.