People across the West Midlands are being urged to add their names to the NHS Organ Donor Register, as part of a national recruitment campaign.
Currently 1,677 people across the region urgently need an organ transplant.
Of these 1,546 need a kidney, 33 a liver, 33 a lung, 14 a heart and four require a combined heart and lung transplant.
Just over one in five people (22 per cent) have pledged to give their organs, either after death or as a living donor, compared with the one in three (29 per cent) in Scotland and the West Country.
Today 2.9 million homes will receive a leaflet inviting people to join the register as part of UK Transplant's My Life, My Gift campaign. To date nearly 15 million people have signed up to become a donor.
Last year more than 3,000 lives were saved through organ donation, nearly a third of which (905) were Midlands patients.
Conversely 63 people in the region died before receiving a transplant, and there is also a severe shortage of donors from black and Asian communities.
* More information at www.mylifemygift.org or call UK Transplant's Organ Donor Line on 0845 60 60 400