Midland A&E units have the third highest level of admissions due to alcohol in the country, which have doubled in a decade, according to new NHS figures.
In 2006/07 the region's hospitals admitted 20,650 - one in ten of all admissions in England, which have risen from 93,459 in 1995/96 to 207,788 in the last financial year.
Worcestershire Primary Care Trust recorded the highest number of hospital admissions, due to alcohol-related diseases, with 1,994 in 2006/07.
Birmingham’s PCTs totalled 5,333 during the same period - South Birmingham (1,882), Birmingham East and Northern (1,701) and Heart of Birmingham (1,750) - representing a quarter of the regional total.
Shropshire County PCT (796) and Solihull (647) recorded the lowest number of alcohol-related admissions in the region.
The figures, published by the NHS Information Centre, also revealed the number of people admitted, where primary or secondary diagnosis was linked to drink had risen seven per cent on the 193,637 admissions in 2005/06.
Nigel Smith, spokesman for Department of Health (West Midlands), said: "Obviously we are concerned, but this increase has occurred across the country, not just in our region.
"Birmingham is one of the worst areas in the UK, but through a Local Area Agreement - with primary care trusts, local authorities and police - the West Midlands is working towards specific targets, one of which is to cut the number of alcohol-related admissions."
Nationally, a breakdown revealed there were 57,142 NHS hospital admissions with a primary diagnosis specifically related to alcohol in 2006/07, up 52 per cent since 1995/96.
Tim Straughan, chief executive of the NHS Information Centre, said: "This report shows alcohol is placing an increasing burden right across the NHS - from the GP surgery to the hospital bed.
"These rises paint a worrying picture about the relationship between the population and the bottle."
An Alcohol Concern spokesman said: "The new figures showing a rise in alcohol-related hospital admissions confirm everything we’ve heard from the frontline staff who deal with the after effects of heavy drinking.
"What is however particularly dispiriting is the news that the number of people who aren’t familiar with the recommended limits has actually gone up.
"The Government needs to shape a response that meets the challenges thrown up by this bulletin."
Andrew Lansley, the shadow health secretary, said: "It is particularly worrying that so many under 18s are ending up in hospital because they’ve had too much to drink.
"Tackling issues like excessive drinking is a social responsibility in which we all have a part to play. But the Government has failed to show the leadership and cultural change we need."