Christian Malcolm will launch his World Championship bid today when he competes in the heats of the 200metres in Helsinki.
The 26-year-old will be joined by Coventry's Marlon Devonish and the pair will be looking to ensure there is at least one Briton in the final.
The absence of a British athlete from Sunday night's 100m final, for only the second time in the championships' history, came after Devonish and Jason Gardener were eliminated at the semi-final stage.
Gardener and Mark Lewis-Francis fell at the same stage in Athens last year where there were also no British competitors in the 200m final. Malcolm and Devonish will be aiming to reverse that trend.
Malcolm arrives in Finland seventh in the world rankings after he recorded 20.15 seconds at the European Cup in June.
The Cardiff athlete finished fifth at the Sydney Olympics before reaching both sprint finals at the World Championships in Edmonton a year later, finishing fifth and seventh in the 100m and 200m respectively.
His career has since stalled, injuries and illness taking a toll, and the personal bests he recorded in Canada in 2001 still stand.
He has sustained ankle, toe and hamstring injuries as well as life-threatening kidney failure prior to the Games in Athens.
This year, Malcolm won the 200m at the trials and finished third in the 100m, before he sustained a pelvic injury, treatment for which delayed his arrival in Helsinki.
On paper, Malcolm seems to be in with a good chance of making the final.
It is likely to be a young field with 100m champion Justin Gatlin the oldest at 23 of the leading contenders who included Spearmon, American team-mate Tyson Gay and Jamaica's Usain Bolt. Malcolm and 29-yearold Devonish are considered outsiders.
Devonish will be looking to put his 100m disappointment behind him as he doubles up at a major championships for the first time.
He won the 200m world indoor title in 2003, and has also picked up individual medals at European and Commonwealth level as well as running the third leg for the victorious 4x100m squad in Athens last year.
Although he has already reached a World Championship 200m final, when he was eighth in Edmonton, the Tony Lester-trained athlete faces a challenge to do so in Helsinki.
With a season's best time of 20.41secs, Devonish may need to get near his threeyearold personal best of
20.19secs just to reach the final.
Should either advance, it will give British sprinting a timely spur after Gardener, Devonish and former world junior champion Lewis-Francis were eliminated in the second round of the 100m.
In terms of the sprint relay, Lewis-Francis is still feeling his hamstring, while Chris Lambert is hoping to recover from injury.
Also present in Helsinki is Craig Pickering, who led a British clean sweep in the 100m in the European Junior Championships last month.
The 18-year-old ran could run a relay leg in the heats.