England's reign as Hong Kong Sixes champions came to an end as India comfortably disposed of the West Indies in the final to claim the trophy and the $100,000 first prize.
Robert Croft's team was eliminated in the semi-finals by the West Indies when they were unable to overhaul a total of 72 for three, in which Lendl Simmons top scored with 25 runs.
England's response with the bat was disappointing, despite Chris Read's impressive 27 off just nine balls looking like it would give the back-to-back winners a solid opportunity to make it three titles in row.
But three wickets were lost for the addition of just two runs to leave England struggling, falling six runs short of the West Indies' total as they failed to qualify for the final for the first time in four years.
"Obviously we're a bit disappointed," said England's Worcestershire bowler Kabir Ali. "We could have done a better job. We did a decent job with the ball but, with the batting, we sort of collapsed there in the middle after the good start we had."
India progressed to the final with a four-wicket win over Sri Lanka before comfortably overcoming the West Indies to take the trophy for the first time.
With the teams bowling five eight-ball overs in the final as opposed to the regular six-ball variety delivered during the earlier rounds of the competition, the West Indies' total of 72 for one never looked like being enough.
Former one day international star Robin Singh led by example for the Indians, scoring 34 off 15 balls before retiring, leaving Hrishikesh Kanitkar to hit the winning runs with six balls remaining.