The FA Cup fourth round could host an explosive West Midland derby - if West Bromwich Albion and Birmingham City can win their respective replays.
The draw has been kind to Aston Villa who will face League One strugglers Port Vale at Villa Park.
Coventry's reward for victory over Brighton is a tie against either near neighbours Nuneaton or Premiership Middlesbrough at the Ricoh Arena.
Non-league Tamworth will face Walsall if both sides can overcome Stoke and Barnsley respectively in replays.
Wolves will play Manchester United at Molineux - provided Sir Alex Ferguson's side can get past Burton Albion at the second attempt.
Draw in full:
Stoke or Tamworth vs Barnsley or Walsall
Cheltenham or Chester vs Newcastle United
Coventry City vs Nuneaton or Middlesbrough
WBA or Reading vs Torquay or Birmingham City
Portsmouth vs Liverpool
Leicester City vs Southampton
Bolton Wanderers vs Arsenal
Aston Villa vs Port Vale
Brentford vs Sunderland
Manchester City vs Wigan or Leeds United
Millwall or Everton vs Chelsea
Preston North End vs Crystal Palace
West Ham United vs Blackburn Rovers
Colchester United vs Derby County
Charlton Athletic vs Leyton Orient
Wolverhampton Wanderers vs Burton Albion or Manchester United
Ties to be played weekend of January 28/29th January