England prop Matt Stevens has been ruled out of tomorrow's Six Nations Championship clash against Ireland after suffering a recurrence of the shoulder injury which kept him out of the 18-12 defeat by Scotland three weeks ago.
The Bath forward will be replaced in the front row by Leicester's Julian White, one of five World Cup winners originally dropped for the match at Twickenham.
Perry Freshwater is called up to the replacements bench.
White was one of six World Cup winners axed by head coach Andy Robinson after last Sunday's defeat to France in Paris, with Stevens switched to tighthead prop and Andrew recalled.
But White gains an unexpected recall, winning his 33rd cap, with Perpignan prop Freshwater summoned for duty.
Robinson said: "I am disappointed for Matt but it also gives Julian another opportunity to start.
"Perry has been part of the squad for some time now and I had no hesitation in bringing him on to the bench."
England are striving to avoid suffering three successive Six Nations defeats for the second season in a row and look certain to miss Stevens' power and mobility against a Triple Crown-chasing Irish side.
Match referee Joel Jutge has also been forced out by injury, and will be replaced by Wales' Nigel Whitehouse, with Nigel Owens taking over from Whitehouse as touch judge.
Owens had been due to run the line in Rome, where Italy host Scotland tomorrow, but his touch judge's role goes to England's Wayne Barnes.
Hooker Lee Mears, meanwhile, chosen for his first international start after Robinson's decision to make changes, defended his team-mates after successive defeats to Scotland and France. "I don't think you become a bad side overnight," said Mears who replaced Steve Thompson during the match. "It was a culmination of things last weekend and we were very disappointed but hopefully we can come out stronger and put it all right."
Mears cannot wait to run out at Twickenham, saying: "The first start's massive, it's everything I've aimed for since I was a young boy. It's what we all dream about so to get the chance to wear the number two on my back is a big occasion - and at Twickenham."