Bulldozers and diggers have started flattening the former Birmingham home of the BBC to make way for a #100 million science and technology park.
The landmark Pebble Mill building is being torn down as part of a demolition programme by Birmingham-based specialists DSM, which should be complete by November.
The park is expected to be home to world-class research and development facilities for the medical and healthcare industries.
Regional development agency Advantage West Midlands, which has a 95-year lease on the site from Calthorpe Estates, is looking for potential occupants for the first phase of the park. The development links into the Central Technology Belt, a hightechnology corridor running along the A38 between Aston Science Park and Malvern Science Park.
Pebble Mill was the home of the BBC in Birmingham for 33 years before moving to new studios and offices at the Mailbox last year.
Advantage West Midlands chief executive John Edwards said: "I have mixed feeling from seeing Pebble Mill being demolished. While it means the loss of an historic landmark building for the city, it also means a new era with an exciting hightechnology future. The recent situation at MG Rover makes the progress made with our infrastructure projects in the Central Technology Belt all the more encouraging."