Accountancy firm Friend is moving to one of the city's most striking locations - Quayside in Birmingham's Convention Quarter on Broad Street.
The move, which takes place on August 30, is part of its continued growth and expansion.
It becomes the office scheme's second tenant of this year - only two months after a deal with transport engineers, Alstom, was announced.
The corporate finance and tax specialists are relocating from Edgbaston to Kenmore's 100,000 sq ft refurbished, landmark tower - home to Yell, who took some 21,000 sq ft in one of the city's biggest office deals of 2004.
Friend will occupy the 11th floor - some 6,318 sq ft - at £18 per sq ft on a five year lease, leaving 63,180 sq ft remaining, available in suites from 3,000 sq ft upwards.
"For Friend, Quayside provides the ideal solution - high spec Grade A accommodation, ample parking provision, bird's eyei views across the city and the scope to expand on-site," said John Hammond of agents GSD.
"Last year Kenmore completed a £10 million makeover of this famous landmark building transforming the 1960s block into a desirable address. The resulting accommodation is attracting growing interest from high profile, blue chip clients seeking value for money accommodation in the City core."
A spokesman for Friend said: "This is another exciting phase of our development"
Joint agents with GSD are Colliers CRE.