The Leicestershire-based agency has been charged with finding a mix of high-quality, independent boutique retailers and specialist food and beverage operators to the new estate.
The Village is a mixed-use commercial and residential scheme centred around Greenfield Crescent between Calthorpe Road and Harborne Road in Edgbaston.
Jayne Herritty, sales and marketing director for Calthorpe Estates, said: "Having reached a stage of this flagship project where we are ready to engage with prospective tenants, it was incredibly important to us that the agents for The Village.
"Not only does Space have an enviable reputation in the commercial property market for its specialist retail and leisure experience, the team shares our passion and vision for The Village and we are confident they will be great advocates for the project when presenting the commercial opportunities to potential occupiers."
The Space team for The Village is headed up by managing director Peter Leverett and director Martin Herbert, with support from surveyor Naomi Ellwood.
Mr Leverett said: "Getting the leisure and retail mix right is key to creating a distinctive sense of place for The Village and the focus for Space is firmly on complementing the nature of the existing offering in Edgbaston - serving those who live and work in the area while also establishing The Village as a destination in its own right.
"We will be working closely with the likes of homewares and interiors businesses, specialist food and beverage operators to niche or designer retailers, as we help build the new leisure and retail community."